I have the same proble....PLease someone help I know it's not DRM because AnyDVD does report that the disk has no protection. Every DVD I have tried is producing the same errors but in different spots. None of them get more than 5 seconds into the process. These are childrens DVD movies (Abby Kadabby, Elmo, Cudoroy, etc). The machine in question is a brand new (one month old) Dell Studio XPS running Vista 64 bit Ultimate, it's super quick with an i7 and 6gb of memory and unfortunately I can't use it. I have to use AnyDvd from my old / slow XP laptop and then copy the image accross my network to the Dell box to manipulate it. The other thing I can tell you is the application is OK with analizing the DVD. but when I look in the hardware section of my DVD drive it says.... "Windows did not start a related device driver. To learn more, click the Driver tab and then click Driver Details." The driver that's not loaded is the AnyDvd driver. I'm thinking this may have something to do with the problem.